• Home
  • BEST4 Screening Trial
    • BEST4 Screening Trial
    • Taking Part
    • Trial Data Use
    • After the Trial
    • BEST4 Screening Trial FAQ
    • Important Information
    • BEST4 Screening Updates
  • BEST4 Surveillance Trial
    • BEST4 Surveillance Trial
    • Taking Part
    • Trial data use
    • Surveillance updates
    • FAQs
  • The Capsule Sponge
    • The Capsule Sponge
    • Health problems
    • Capsule Sponge FAQs
  • About
  • Contact
  • Clinical Resources
    • Clinical Resources
    • Trial Design
    • Capsule Sponge Technology

BEST4: In partnership with the NHS

BEST4: Discovering ways to find and prevent heartburn-related health problems

BEST4 is running two trials to discover ways to find heartburn-related health problems and prevent oesophageal cancer.

 The BEST4 Screening Trial is offering 40,000 people with heartburn, indigestion, or acid reflux the capsule sponge test. This is to see if the test can help find heartburn-related problems, such as Barrett’s Oesophagus, earlier and improve long-term health. If the test reduces the side-effects and deaths from oesophageal cancer it could be used as part of a National Screening Programme. 

More about the BEST4 Screening Trial

BEST4 Screening Trial

The BEST4 Surveillance Trial is for people who already have a diagnosis of Barrett’s Oesophagus aiming to see if the capsule sponge test can be used for monitoring of any signs of dysplasia (cell changes prior to cancer) or cancer. If the test works, it could be used in Barrett’s surveillance to reduce the number of endoscopies needed.  

More about the BEST4 Surveillance Trial

BEST4 Surveillance Trial

The Capsule Sponge Test:  

The BEST4 trials are exploring the use of the capsule sponge test, a quick and simple way to check the health of your oesophagus (food pipe). 

Learn more about the capsule sponge test.

Research collaborators

Funders

Social

Copyright © 2025 BEST4TRIAL - All Rights Reserved.


This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

DeclineAccept