BEST4 Screening Trial FAQs

Please use the link in your appointment confirmation text to cancel an existing appointment.  

Please use the link in your appointment confirmation text to reschedule an existing appointment.  

EMS Healthcare will be providing the mobile units and nurses for the capsule sponge appointments as part of the BEST4 Screening Trial.   

You can take your normal medication prior to the appointment, however if you take blood-thinning medication, please check the stopping instructions.  

Yes the capsule sponge tests manufacturer name is Endosign. There is also a very similar device in the UK called the Cytosponge.  

Negative result – the capsule sponge test showed no signs of cell changes. No further tests are needed.  

Insufficient result - capsule sponge test did not give a clear result. This is nothing to worry about, but we are inviting you to have a repeat test. 

Positive result – there are some changes in the cells collected. We recommend that you have an endoscopy to confirm the cause of these cell changes. This is nothing to be worried about but it is good to check the changes. In many cases, these health problems do not need further follow-up. After your endoscopy you will be given advice on any further tests or treatment needed. 

 If you have not received your results within 8 weeks, please contact the study team on  01223 761085 or  cuh.best4.trial@nhs.net 

Please call our study team on 0808 281 4772 and they will assist you to find the mobile unit.

No.  

Yes. Please do not have anything to eat or drink for at least 4 hours before the procedure. If you need to take medication, please only take this with small sips of water.  

Yes you can. Please provide this information to the nurse on the day of your appointment. If you would like to discuss this beforehand, please call our study team on 0808 281 4772.  

Please call the study team on 0808 281 4772 and we will try our best to accommodate an appointment for you if the nearest mobile unit.  

No.

The nurses will ask you medical and heartburn health related questions such as; the medication you are taking for your symptoms, medical history, etc.  

Cyted Ltd, is providing laboratory services for the BEST4 trials.   

We greatly appreciate any feedback you have. Please send this to cuh.best4screening@nhs.net .  

Unfortunately, we are unable to accept self-referrals at present, however please register interest with our study team on  cuh.best4screening@nhs.net and we will update you if this changes.   

 That is fine. You are welcome to withdraw from the trial at any point. Please contact our clinic team on  cuh.best4screening@nhs.net or 0808 281 4772  

 Yes. The mobile unit is wheelchair friendly. Please contact the trial team on 0808 281 4772 prior to you appointment.  

Yes. The mobile unit will be located with close-by toilet facilities.  

This is not a problem. Please call the team on 0808 281 4772 after you have booked your appointment and we can arrange for a translator telephone service to assist you throughout your appointment.  

 Due to the size of the facilities and friend or family member can only join you during your appointment when a witness is required to be present during the informed consent process.  A witness is typically required for participants who can understand the study and give their consent verbally, but not able to sign the consent form, for example:  

• The participant is illiterate   
• The participant is visually impaired  
• The participant is physically disabled.  

Please inform the team if you will be bringing a friend or family member for one of the reasons above on 0808 281 4772  or cuh.best4screening@nhs.net  prior to arriving for our appointment.

A family or friend member may wait in the car or at the local facilities (eg. supermarket) during your appointment.